Andrea Darling (née Smithson) is the mother of Brian Darling's illegitimate child, Brian Jr.

She leaves her son with Brian while away in Brazil, initially much to Brian's annoyance. However, upon her return, he is unwilling to give up his role as a father. During the proceeding custody struggle, Brian discovers that Andrea has been visiting Brazil for an unconventional cancer treatment and that she has been hiding her sickness from their son.

She eventually agrees to enter a medical trial that turns out to be ineffective. As Andrea's illness worsens, Brian finds himself drawing closer to her, and eventually asks her to marry him. After what Brian regards a sign from God, Andrea miraculously recovers, and is able to start planning her life together with Brian and her son.